Upcoming CfA seminars

3rd October 2019: Vanessa Murphy

Personalised biomarker-driven management of asthma in pregnancy and its influence on childhood respiratory health

Speaker: Dr. Vanessa Murphy, University of Newcastle and the Hunter Medical Research Institute, Newcastle, Australia
 

Time: 16:00, 3rd October 2019
Venue: Biomedicum Lecture Hall 3 (A0325), Entrance Level, Solnavägen 9, KI Campus Solna
Hosts: Bronwyn Haasdyk Brew and Catarina Almqvist Malmros, Dept. of Medical Epidemiology and Biostatistics
Coffee and tea served 15:30

Welcome!

About the speaker:

Dr. Vanessa Murphy

The trial brings together a multi-disciplinary team from Respiratory Medicine, Obstetrics, Neonatology, Midwifery, Paediatrics, Dietetics, Psychology and Health Economics.

Her research goal is to generate the evidence required to change clinical practice in the area of asthma management in pregnancy.

Relevant publications

1. Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia J, Gibson PG. A meta-analysis of adverse perinatal outcomes in women with asthma. British Journal of Obstetrics and Gynaecology 2011; 118(11):1314-23.

2. Powell H, Murphy VE, DR Taylor, MJ Hensley, K McCaffery, W Giles, VL Clifton, PG Gibson. Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomized controlled trial. Lancet 2011, 378: 983-990.

3. Mattes J, Murphy VE, Powell H, Gibson PG. Prenatal origins of respiratory infections: Protective effect of optimised asthma management during pregnancy. Thorax, 2014; 69(4): 383-4.

4. Morten M, Collison A, Murphy VE, Barker D, Oldmeadow C, Attia J, Meredith J, Powell H, Robinson PD, Sly PD, Gibson PG, Mattes J. Managing Asthma in Pregnancy (MAP) trial: FeNO levels and childhood asthma. J Allergy Clin Immunol 2018. 142(6):1765-1772.

5. Murphy VE, Jensen ME, Robijn AL, Wright TK, Mattes J, Collison A, Gibson PG. How maternal BMI modifies the impact of personalised asthma management in pregnancy. Accepted by JACI In Practice 21/6/2019.

The Asthma and Allergy Association's Research Foundation welcomes applications for research grants

The Swedish Asthma and Allergy Association's Research Foundation (Astma och Allergiförbundets Forskningsfond) supports scientific research on asthma, allergies and other hypersensitivities.

Applications for research grants 2019 can now be submitted.

The research foundation supports research projects that have a clear clinical and patient-oriented focus and the final goal should be to increase the quality of life of persons with allergic diseases. Normally, the grants are in the size of 200 000 - 250 000 SEK per year.

Application deadline 22nd September.

Read more on the site of the Asthma and Allergy Association's Research Foundation (in Swedish)

The Swedish Association for Allergology (SFFA) national conference 4th October 2019
"The oral route - a highway to health"

The Swedish Association for Allergology (SFFA) will organise an "Allergy Day" on 4th October 2019 in Stockholm, with the theme "The oral route - a highway to health". In order to participate you need to be a member of SFFA.

More information and link to the programme on SFFA's website

Aii grants available for the organisation

of workshops and minisymposia 

in the area of

Allergy, immunology and inflammation

The doctoral programme Aii (Allergy, immunology and inflammation) announces GRANTS available for the organization of workshops and minisymposia in the area of Allergy, immunology and inflammation

Please contact Caroline Grönwall, chair of the Aii program, or Jan Wahlström, program coordinator, for more information about requirements and how you can apply.

Costs that may be covered include travel and accommodation for invited speakers, rent of venue, lunches and coffee breaks etc.

Recent publications by CfA researchers

Cryptococcus neoformans Induces MCP-1 Release and Delays the Death of Human Mast Cells. Lopes JP, Stylianou M, Backman E, Holmberg S, Ekoff M, Nilsson G, Urban CF. Front Cell Infect Microbiol. 2019 Aug 13;9:289. doi: 10.3389/fcimb.2019.00289. eCollection 2019.

DNA Methylation Trajectories During Pregnancy. Gruzieva O, Merid SK, Chen S, Mukherjee N, Hedman AM, Almqvist C, Andolf E, Jiang Y, Kere J, Scheynius A, Söderhäll C, Ullemar V, Karmaus W, Melén E, Arshad SH, Pershagen G. Epigenet Insights. 2019 Aug 13;12:2516865719867090. doi: 10.1177/2516865719867090. eCollection 2019.

Carriers of a classic CYP21A2 mutation have a reduced mortality. A population-based national cohort study. Nordenström A, Svensson J, Lajic S, Frisén L, Nordenskjöld A, Norrby C, Almqvist C, Falhammar H. J Clin Endocrinol Metab. 2019 Aug 8. pii: jc.2019-01199. doi: 10.1210/jc.2019-01199.

New biological treatments for asthma and skin allergies. Eyerich S, Metz M, Bossios A, Eyerich K. Allergy. 2019 Aug 23. doi: 10.1111/all.14027.

The Human Microbiota and Its Relationship with Allergies. Fyhrquist N. Gastroenterol Clin North Am. 2019 Sep;48(3):377-387. doi: 10.1016/j.gtc.2019.04.005. Epub 2019 Jun 25. Review.

Personalized medicine and back-allogeneic exosomes for cancer immunotherapy. Samuel M, Gabrielsson S. J Intern Med. 2019 Jul 29. doi: 10.1111/joim.12963. [Epub ahead of print] Review.

Individually dosed omalizumab facilitates peanut oral immunotherapy in peanut allergic adolescents. Brandström J, Vetander M, Sundqvist AC, Lilja G, Johansson SGO, Melén E, Sverremark-Ekström E, Nopp A, Nilsson C. Clin Exp Allergy. 2019 Jul 22. doi: 10.1111/cea.13469.

Lost in the transition from pediatric to adult healthcare? Experiences of young adults with severe asthma. Ödling M, Jonsson M, Janson C, Melén E, Bergström A, Kull I. J Asthma. 2019 Jul 22:1-9. doi: 10.1080/02770903.2019.1640726.

Maternal and paternal atopic dermatitis and risk of atopic dermatitis during early infancy in girls and boys. Endre KMA, Rehbinder EM, Carlsen KL, Carlsen KH, Gjersvik P, Hedlin G, Jonassen CM, LeBlanc M, Nordlund B, Skjerven HO, Staff AC, Söderhäll C, Vettukattil R, Landrø L; study group. J Allergy Clin Immunol Pract. 2019 Jul 15. pii: S2213-2198(19)30613-0. doi: 10.1016/j.jaip.2019.06.039.

The GALEN rhinosinusitis cohort: chronic rhinosinusitis with nasal polyps affects health-related quality of life. Khan A, Huynh TMT, Vandeplas G, Joish VN, Mannent LP, Tomassen P, van Zele T, Cardell LO, Arebro J, Olze H, Forster-Ruhrmann U, Kowalski ML, Olszewska-Ziaber A, Fokkens W, van Drunen C, Mullol J, Alobid I, Hellings PW, Hox V, Toskala E, Scadding G, Lund V, Bachert C. Rhinology. 2019 Jul 18. doi: 10.4193/Rhin19.158.

Association between pharmacotherapy for ADHD in offspring and depression-related specialty care visits by parents with a history of depression. Chen Q, Larsson H, Almqvist C, Chang Z, Lichtenstein P, D'Onofrio BM, Ludvigsson JF. BMC Psychiatry. 2019 Jul 17;19(1):224.

Patient journey and treatment patterns in adults with IPF based on health care data in Sweden from 2001 to 2015. Sköld CM, Arnheim-Dahlström L, Bartley K, Janson C, Kirchgaessler KU, Levine A, Ferrara G. Respir Med. 2019 Aug;155:72-78. doi: 10.1016/j.rmed.2019.06.001.

Venom immunotherapy in patients with clonal mast cell disorders: IgG4 correlates with protection. Jarkvist J, Salehi C, Akin C, Gülen T. Allergy. 2019 Jul 15. doi: 10.1111/all.13980.

CD203c distinguishes the erythroid and mast cell-basophil differentiation trajectories among human FcεRI+ bone marrow progenitors. Grootens J, Ungerstedt JS, Wu C, Hamberg Levedahl K, Nilsson G, Dahlin JS. Allergy. 2019 Jul 15. doi: 10.1111/all.13981.

Allergen components in diagnosing childhood hazelnut allergy: systematic literature review and meta-analysis. Nilsson C, Berthold M, Mascialino B, Orme M, Sjölander S, Hamilton R. Pediatr Allergy Immunol. 2019 Jul 13. doi: 10.1111/pai.13110.

Oral Food Challenge Implementation: The First Mixed-Methods Study Exploring Barriers and Solutions. Hsu E, Soller L, Abrams EM, Protudjer JLP, Mill C, Chan ES. J Allergy Clin Immunol Pract. 2019 Jul 10. pii: S2213-2198(19)30607-5. doi: 10.1016/j.jaip.2019.06.034.

Allergenomics of the tick Ixodes ricinus reveals important α-Gal-carrying IgE-binding proteins in red meat allergy. Apostolovic D, Mihailovic J, Commins SP, Wijnveld M, Kazimirova M, Starkhammar M, Stockinger H, Platts-Mills TAE, Cirkovic Velickovic T, Hamsten C, van Hage M. Allergy. 2019 Jul 13. doi: 10.1111/all.13978.

Allogenicity Boosts Extracellular Vesicle-Induced Antigen-Specific Immunity and Mediates Tumor Protection and Long-Term Memory In Vivo. Larssen P, Veerman RE, Akpinar GG, Hiltbrunner S, Karlsson MCI, Gabrielsson S. J Immunol. 2019 Aug 15;203(4):825-834. doi: 10.4049/jimmunol.1801628. Epub 2019 Jul 10

Enhanced local production of IL-26 in uncontrolled compared with controlled adult asthma. Tufvesson E, Jogdand P, Che KF, Levänen B, Erjefält JS, Bjermer L, Lindén A. J Allergy Clin Immunol. 2019 Jul 6. pii: S0091-6749(19)30902-9. doi: 10.1016/j.jaci.2019.06.035.

Long-term dietary fiber intake and risk of chronic obstructive pulmonary disease: a prospective cohort study of women. Szmidt MK, Kaluza J, Harris HR, Linden A, Wolk A. Eur J Nutr. 2019 Jul 6. doi: 10.1007/s00394-019-02038-w.

Tackling the Complexity of the Exposome: Considerations from the Gunma University Initiative for Advanced Research (GIAR) Exposome Symposium. Zhang P, Arora M, Chaleckis R, Isobe T, Jain M, Meister I, Melén E, Perzanowski M, Torta F, Wenk MR, Wheelock CE. Metabolites. 2019 Jun 6;9(6). pii: E106. doi: 10.3390/metabo9060106.

Divergent Effects of Acute and Prolonged Interleukin 33 Exposure on Mast Cell IgE-Mediated Functions. Rönnberg E, Ghaib A, Ceriol C, Enoksson M, Arock M, Säfholm J, Ekoff M, Nilsson G. Front Immunol. 2019 Jun 19;10:1361. doi: 10.3389/fimmu.2019.01361. eCollection 2019.

Upcoming conferences and meetings
in the asthma and allergy area

ERS International Congress, 28 September-2 October 2019, Madrid, Spain

KiiM retreat, 3-4 October 2019, Skoghem and Wijk, Lidingö

EAACI PAAM (Pediatric Allergy and Asthma Meeting), 17-19 October 2019, Florence, Italy

16th International Conference "Bioactive Lipids in Cancer, Inflammation and Related Diseases", 20-23 October 2019, St. Petersburg, Florida, USA

ERS Research Seminar "Early Origins of Lung Disease: an interdisciplinary approach", 11-12 November 2019, Lisbon, Portugal

EAACI ISMA (International Symposium on Molecular Allergology), 28-30 November 2019, Amsterdam, the Netherlands

EAACI Allergy School on Food Allergy, 5 - 7 December 2019, Paris, France

EAACI Winter School 2020 Basic Immunology Research in Allergy and Clinical Immunology, 23 - 26 January 2020, Chamonix, France

ERS Satellite Symposium, 20 February 2019:
COPD - Prevention of exacerbations and new treatment pathways in COPD
ASTHMA - Prevention of exacerbations and oral steroid use in Asthma

ERS Lung Science Conference - Metabolic alterations in lung ageing and disease, 5-8 March 2020, Estoril, Portugal

AAAAI Annual Meeting, 13-16 March 2020, Philadelphia, USA

ATS International Conference, 15-20 May 2019, Philadelphia, USA