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The Centre for Allergy Research

Newsletter 13 March 2020

 

The Swedish Society for Allergology (SFFA) welcomes applications for this year's large stipend


The Swedish Society for Allergology (SFFA) awards research stipends each year to stimulate allergy and asthma research in Sweden. It is now possible to apply for this year's stipend. The winner of the stipend will receive the award at SFFA's annual conference in Stockholm, 8th May 2020.

More information and details on how to apply are available here.

Application deadline: 31st March 2020

 

The Asthma and Allergy Association's Research Foundation announces new research grants to address knowledge gaps

 

The Asthma and Allergy Association's Research Foundation announces new research grants. The grants focus on knowledge gaps that the Research Foundation has identified in the allergy and asthma area, and that the Foundation wants to support in particular. The grants will be up to a maximum of 1 million SEK per year for a maximum period of 5 years. In total, the Research Foundation will announce 10 million SEK for the 5 year period.

Application period: 14 February - 16 March 2020

More information about the grants and how to apply

 

Half-time seminar


24th March: Willem Abma
Institute of Environmental Medicine

Title: Experimental studies of lipid mediator modulation of airway responsiveness

Main supervisor: Craig Wheelock, Co-supervisors: Mikael Adner, Sven-Erik Dahlén

Time: 13:00
Venue: Meeting room Lars. E. Gustafsson (D1012), Biomedicum, Solnavägen 9

 

Component handbook "Molecular (component-based) allergy diagnotiscs with focus on food allergy"

is now available


The third version of the component handbook: "Molecular (component-based) allergy diagnotiscs with focus on food allergy" is now available. This version has been prepared by the Competence Centre Paediatric Food Allergy at the Sachs' Children and Youth Hospital, together with 17 clinically active co-authors. The manual is not a complete scientific account of the area, but rather based on own experiences and scientific literature.

The handbook is thought to be used in clinical praxis to the benefit of patients, and as a guide for improved and more targeted allergy diagnostics. The handbook will not be printed, but is available online.

Editors: Anna Nopp and Caroline Nilsson

The component handbook

 

ERS funding opportunities

 

ERS Short Term Research Fellowships, deadline 1st April 2020

ERS Clinical Training Fellowships, deadline 1st April 2020

ERS RESPIRE Marie Sklodowska-Curie Postdoctoral Research Fellowships, deadline 1st May 2020

 

Recent publications by CfA researchers

 

Lipoxin A4 reduces house dust mite and TNFα-induced hyperreactivity in the mouse trachea. Abma W, Noreby M, Wheelock CE, Dahlén SE, Adner M, Säfholm J. Prostaglandins Other Lipid Mediat. 2020 Feb 15:106428. doi: 10.1016/j.prostaglandins.2020.106428.

Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial. Skjerven HO, Rehbinder EM, Vettukattil R, LeBlanc M, Granum B, Haugen G, Hedlin G, Landrø L, Marsland BJ, Rudi K, Sjøborg KD, Söderhäll C, Staff AC, Carlsen KH, Asarnoj A, Bains KES, Carlsen OCL, Endre KMA, Granlund PA, Hermansen JU, Gudmundsdóttir HK, Hilde K, Håland G, Kreyberg I, Olsen IC, Mägi CO, Nordhagen LS, Saunders CM, Skrindo I, Tedner SG, Værnesbranden MR, Wiik J, Jonassen CM, Nordlund B, Carlsen KCL. Lancet. 2020 Feb 19. pii: S0140-6736(19)32983-6. doi: 10.1016/S0140-6736(19)32983-6.

Endotypes of chronic rhinosinusitis: Impact on management. Cardell LO, Stjärne P, Jonstam K, Bachert C. J Allergy Clin Immunol. 2020 Mar;145(3):752-756. doi: 10.1016/j.jaci.2020.01.019. Epub 2020 Jan 28

Familial Coaggregation of Asthma and Type 1 Diabetes in Children. Smew AI, Lundholm C, Sävendahl L, Lichtenstein P, Almqvist C. JAMA Netw Open. 2020 Mar 2;3(3):e200834. doi: 10.1001/jamanetworkopen.2020.0834.

Smoking and snuff use in pregnancy and the risk of asthma and wheeze in pre-school children - a population-based register study. Lundholm C, Gunnerbeck A, D'Onofrio BM, Larsson H, Pershagen G, Almqvist C. Clin Exp Allergy. 2020 Mar 9. doi: 10.1111/cea.13593.

Qualitative analysis of perceived impacts on childhood food allergy on caregiver mental health and lifestyle. Abrams EM, Simons E, Roos L, Hurst K, Protudjer JLP. Ann Allergy Asthma Immunol. 2020 Mar 4. pii: S1081-1206(20)30113-7. doi: 10.1016/j.anai.2020.02.016.

Clinical and serological characterization of the α-Gal syndrome - importance of atopy for symptom severity in a European cohort. Kiewiet MBG, Apostolovic D, Starkhammar M, Grundström J, Hamsten C, van Hage M. J Allergy Clin Immunol Pract. 2020 Mar 3. pii: S2213-2198(20)30176-8. doi: 10.1016/j.jaip.2020.02.016.

Early-life antibiotic use and risk of asthma and eczema: results of a discordant twin study. Slob EMA, Brew BK, Vijverberg SJH, Kats CJAR, Longo C, Pijnenburg MW, van Beijsterveldt TCEM, Dolan CV, Bartels M, Magnusson P, Lichtenstein P, Gong T, Koppelman GH, Almqvist C, Boomsma DI, Maitland-van der Zee AH. Eur Respir J. 2020 Mar 5. pii: 1902021. doi: 10.1183/13993003.02021-2019.

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. Merid SK, Novoloaca A, Sharp GC, Küpers LK, Kho AT, Roy R, Gao L, Annesi-Maesano I, Jain P, Plusquin M, Kogevinas M, Allard C, Vehmeijer FO, Kazmi N, Salas LA, Rezwan FI, Zhang H, Sebert S, Czamara D, Rifas-Shiman SL, Melton PE, Lawlor DA, Pershagen G, Breton CV, Huen K, Baiz N, Gagliardi L, Nawrot TS, Corpeleijn E, Perron P, Duijts L, Nohr EA, Bustamante M, Ewart SL, Karmaus W, Zhao S, Page CM, Herceg Z, Jarvelin MR, Lahti J, Baccarelli AA, Anderson D, Kachroo P, Relton CL, Bergström A, Eskenazi B, Soomro MH, Vineis P, Snieder H, Bouchard L, Jaddoe VW, Sørensen TIA, Vrijheid M, Arshad SH, Holloway JW, Håberg SE, Magnus P, Dwyer T, Binder EB, DeMeo DL, Vonk JM, Newnham J, Tantisira KG, Kull I, Wiemels JL, Heude B, Sunyer J, Nystad W, Munthe-Kaas MC, Räikkönen K, Oken E, Huang RC, Weiss ST, Antó JM, Bousquet J, Kumar A, Söderhäll C, Almqvist C, Cardenas A, Gruzieva O, Xu CJ, Reese SE, Kere J, Brodin P, Solomon O, Wielscher M, Holland N, Ghantous A, Hivert MF, Felix JF, Koppelman GH, London SJ, Melén E. Genome Med. 2020 Mar 2;12(1):25. doi: 10.1186/s13073-020-0716-9.

Adverse pregnancy outcomes and risk of later allergic rhinitis-Nationwide Swedish cohort study. Mitselou N, Hallberg J, Stephansson O, Almqvist C, Melén E, Ludvigsson JF. Pediatr Allergy Immunol. 2020 Feb 14. doi: 10.1111/pai.13230.

Extracellular Vesicles Released From the Skin Commensal Yeast Malassezia sympodialis Activate Human Primary Keratinocytes. Vallhov H, Johansson C, Veerman RE, Scheynius A. Front Cell Infect Microbiol. 2020 Jan 24;10:6. doi: 10.3389/fcimb.2020.00006. eCollection 2020

Sex steroid hormones and asthma in women: state-of-the-art and future research perspectives. Zhang GQ, Bossios A, Rådinger M, Nwaru BI. Expert Rev Respir Med. 2020 Mar 10. doi: 10.1080/17476348.2020.1741351.

The role of gene-environment interactions in lung disease: the urgent need for the exposome. Wheelock CE, Rappaport SM. Eur Respir J. 2020 Feb 6;55(2). pii: 1902064. doi: 10.1183/13993003.02064-2019. Print 2020 Feb.

Activation of metabolite receptor GPR91 promotes platelet aggregation and transcellular biosynthesis of leukotriene C4. Tang X, Fuchs D, Tan S, Trauelsen M, Schwartz TW, Wheelock CE, Li N, Haeggström JZ. J Thromb Haemost. 2020 Jan 13. doi: 10.1111/jth.14734.

Research Priorities in Pediatric Asthma: Results of a Global Survey of Multiple Stakeholder Groups by the Pediatric Asthma in Real Life (PeARL) Think Tank. Mathioudakis AG, Custovic A, Deschildre A, Ducharme FM, Kalayci O, Murray C, Garcia AN, Phipatanakul W, Price D, Sheikh A, Agache I, Bacharier L, Bonini M, Castro-Rodriguez JA, De Carlo G, Craig T, Diamant Z, Feleszko W, Ierodiakonou D, Gern JE, Grigg J, Hedlin G, Hossny EM, Jartti T, Kaplan A, Lemanske RF, Le Souef P, Makela MJ, Matricardi PM, Miligkos M, Morais-Almeida M, Pite H, Pitrez PMC, Pohunek P, Roberts G, Sanchez-Garcia S, Tsiligianni I, Turner S, Winders TA, Wong G, Xepapadaki P, Zar HJ, Papadopoulos NG. J Allergy Clin Immunol Pract. 2020 Mar 4. pii: S2213-2198(20)30147-1. doi: 10.1016/j.jaip.2020.01.059.

Towards personalization of asthma treatment according to trigger factors. Niespodziana K, Borochova K, Pazderova P, Schlederer T, Astafyeva N, Baranovskaya T, Barbouche MR, Beltiukov E, Berger A, Borzova E, Bousquet J, Bumbacea RS, Bychkovskaya S, Caraballo L, Chung KF, Custovic A, Docena G, Eiwegger T, Evsegneeva I, Emelyanov A, Errhalt P, Fassakhov R, Fayzullina R, Fedenko E, Fomina D, Gao Z, Giavina-Bianchi P, Gotua M, Greber-Platzer S, Hedlin G, Ilina N, Ispayeva Z, Idzko M, Johnston SL, Kalayci Ö, Karaulov A, Karsonova A, Khaitov M, Kovzel E, Kowalski ML, Kudlay D, Levin M, Makarova S, Matricardi PM, Nadeau KC, Namazova-Baranova L, Naumova O, Nazarenko O, O Byrne PM, Osier F, Pampura AN, Panaitescu C, Papadopoulos NG, Park HS, Pawankar R, Pohl W, Renz H, Riabova K, Sampath V, Sekerel BE, Sibanda E, Siroux V, Sizyakina LP, Sun JL, Szepfalusi Z, Umanets T, Van Bever HPS, van Hage M, Vasileva M, von Mutius E, Wang JY, Wong GWK, Zaikov S, Zidarn M, Valenta R. J Allergy Clin Immunol. 2020 Feb 17. pii: S0091-6749(20)30193-7. doi: 10.1016/j.jaci.2020.02.001.

 

Upcoming conferences and meetings
in the asthma and allergy area

 

Postponed: EAACI Allergy School on Anaphylaxis: Etiology, Prevention and Management, 19-21 March 2020, Izmir, Turkey

Cancelled: Keystone Symposium: Asthma, making new discoveries into better therapies, 2-6 April 2020, Snowbird, Utah, USA

Cancelled: LURN - Lund Respiratory Network meeting, 16-17 April 2020, Ystad, Sweden

Postponed to 16-18 July 2020: WAO International Scientific Conference (WISC), 23-25 April 2020, Rome, Italy

Tolerance Conference, organised by the Swedish Asthma and Allergy Association, 7-8 May 2020, Stockholm, Sweden

ATS International Conference, 15-20 May 2020, Philadelphia, USA

EHRS - European Histamine Research Society Conference, 21-23 May 2020, Düsseldorf/Mühlheim an der Ruhr, Germany

EAACI Congress, 6-10 June 2020, London, UK

8th European Workshop on Lipid Mediators, 24-26 June 2020, Stockholm, Sweden

ERS International Congress, 5-9 September 2020, Vienna, Austria

EUROBAT (European Consortium on Application of Flow Cytometry in Allergy), 15 October 2020, Manchester, UK

FAAM (Food Allergy and Anaphylaxis Meeting), 15-17 October 2020, Manchester, UK

ISAF (International Severe Asthma Forum), 22-24 October 2020, Rome, Italy

 

About the Centre for Allergy Research
The Centre for Allergy Research (CfA) is a centre of excellence at Karolinska Institutet. Our aim is to improve treatment and care of individuals with asthma and allergy. ki.se/cfa

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The Centre for Allergy Research / Centrum för Allergiforskning
Director: Sven-Erik Dahlén, Director Clinical Research: Gunilla Hedlin,
Project Manager: Roelinde Middelveld
kontakt: ki.se/cfa e-mail: cfa@imm.ki.se

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