Recent publications by CfA researchers
Preschool wheezing diagnosis and management-Survey of physicians' and caregivers' perspective. Adamiec A, Ambrożej D, Ryczaj K, Ruszczynski M, Elenius V, Cavkaytar O, Hedlin G, Konradsen JR, Maggina P, Makrinioti H, Papadopoulos N, Schaub B, Schwarze J, Skevaki C, Smits HH, Jartti T, Feleszko W; EAACI Task Force on Clinical Practice Recommendations on Preschool Wheeze. Pediatr Allergy Immunol. 2020 Feb;31(2):206-209. doi: 10.1111/pai.13142. Epub 2019 Nov 18.
Maternal use of nicotine products and breastfeeding 3 months postpartum. Nordhagen LS, Kreyberg I, Eline S Bains K, Carlsen KH, Glavin K, Skjerven HO, Småstuen MC, Hilde K, Nordlund B, Vettukattil R, Hedlin G, Granum B, Jonassen CM, Gudmundsdóttir HK, Haugen G, Maria Rehbinder E, Söderhäll C, Cathrine Staff A, Lødrup Carlsen KC; PreventADALL study group. Acta Paediatr. 2020 Apr 10. doi: 10.1111/apa.15299. [Epub ahead of print]
CD16high CD62Ldim neutrophils induce nerve-mediated airway hyperreactivity. Ekstedt S, Larsson O, Kumlien Georén S, Cardell LO. Clin Exp Allergy. 2020 Mar 20. doi: 10.1111/cea.13602. [Epub ahead of print]
Connectivity patterns between multiple allergen specific IgE antibodies and their association with severe asthma. Roberts G, Fontanella S, Selby A, Howard R, Filippi S, Hedlin G, Nordlund B, Howarth P, Hashimoto S, Brinkman P, Fleming LJ, Murray C, Bush A, Frey U, Singer F, Malby Schoos AM, van Aalderen W, Djukanovic R, Chung KF, Sterk PJ, Adnan C; U-BIOPRED Consortium. J Allergy Clin Immunol. 2020 Mar 15. pii: S0091-6749(20)30341-9. doi: 10.1016/j.jaci.2020.02.031. [Epub ahead of print]
A preseason booster prolongs the increase of allergen specific IgG4 levels, after basic allergen intralymphatic immunotherapy, against grass pollen seasonal allergy. Weinfeld D, Westin U, Hellkvist L, Mellqvist UH, Jacobsson I, Cardell LO. Allergy Asthma Clin Immunol. 2020 Apr 28;16:31. doi: 10.1186/s13223-020-00427-z. eCollection 2020
Sputum microbiome profiles identify severe asthma phenotypes of relative stability at 12-18 months. Abdel-Aziz MI, Brinkman P, Vijverberg SJH, Neerincx AH, Riley JH, Bates S, Hashimoto S, Kermani NZ, Chung KF, Djukanovic R, Dahlén SE, Adcock IM, Howarth PH, Sterk PJ, Kraneveld AD, Maitland-van der Zee AH; U-BIOPRED Study Group. J Allergy Clin Immunol. 2020 Apr 27. pii: S0091-6749(20)30565-0. doi: 10.1016/j.jaci.2020.04.018. [Epub ahead of print
Eosinophils synthesize trihydroxyoctadecenoic acids (TriHOMEs) via a 15-lipoxygenase dependent process. Fuchs D, Tang X, Johnsson AK, Dahlén SE, Hamberg M, Wheelock CE. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Apr;1865(4):158611. doi: 10.1016/j.bbalip.2020.158611. Epub 2020 Jan 7.
NORDSTAR: paving the way for a new era in asthma research. Geale K, Darabi H, Lindh M, Fues Wahl H, Ström O, Cao H, Alvares L, Dodge R, Loefroth E, Altraja A, Backer V, Backman H, Bjermer L, Bossios A, Bøgvald Aarli B, Dahlén B, Hilberg O, Janson C, Kankaanranta H, Karjalainen J, Kauppi P, Kilpeläinen M, Lehmann S, Lehtimäki L, Lundbäck B, Sandström T, Ulrik CS, Sverrild A, Viinanen A, von Bülow A, Yasinska V, Porsbjerg C. Eur Respir J. 2020 Apr 3;55(4). pii: 1902476. doi: 10.1183/13993003.02476-2019. Print 2020 Apr. No abstract available.
Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs. Rao A, Strauss O, Kokkinou E, Bruchard M, Tripathi KP, Schlums H, Carrasco A, Mazzurana L, Konya V, Villablanca EJ, Björkström NK, Lindforss U, Spits H, Mjösberg J. Nat Commun. 2020 Apr 27;11(1):2049. doi: 10.1038/s41467-020-15695-x.
Assessment of Global Lung Function Initiative (GLI) reference equations for diffusing capacity in relation to respiratory burden in the Swedish CArdioPulmonary BioImage Study (SCAPIS). Malinovschi A, Zhou X, Bake B, Bergström G, Blomberg A, Brisman J, Caidahl K, Engström G, Eriksson MJ, Frølich A, Janson C, Jansson K, Vikgren J, Lindberg A, Linder R, Mannila M, Persson HL, Sköld CM, Torén K, Östgren CJ, Wollmer P, Engvall JE. Eur Respir J. 2020 Apr 27. pii: 1901995. doi: 10.1183/13993003.01995-2019. [Epub ahead of print]
Positive Phadiatop Infant (Phinf) can predict allergic disease during childhood. Glaumann S, Lilja G, Nopp A, Nilsson C. Pediatr Allergy Immunol. 2020 Apr 27. doi: 10.1111/pai.13266. [Epub ahead of print]
Handling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI statement. Klimek L, Jutel M, Akdis C, Bousquet J, Akdis M, Bachert C, Agache I, Ansotegui I, Bedbrook A, Bosnic-Anticevich S, Canonica GW, Chivato T, Cruz AA, Czarlewski W, Giacco SD, Du H, Fonseca JA, Gao Y, Haahtela T, Hoffmann-Sommergruber K, Ivancevich JC, Khaltaev N, Knol EF, Kuna P, Larenas-Linnemann D, Melen E, Mullol J, Naclerio R, Ohta K, Okamoto Y, O'Mahony L, Onorato GL, Papadopoulos NG, Pawankar R, Pfaar O, Samolinski B, Schwarze J, Toppila-Salmi S, Shamji MH, Ventura MT, Valiulis A, Yorgancioglu A, Matricardi P, Zuberbier T; ARIA-MASK study group. Allergy. 2020 Apr 24. doi: 10.1111/all.14336. [Epub ahead of print]
Highly sensitive ELISA-based assay for quantification of allergen-specific IgE antibody levels. Karsonova A, Riabova K, Villazala-Merino S, Campana R, Niederberger V, Eckl-Dorna J, Fröschl R, Perkmann T, Zhernov YV, Elisyutina OG, Fedenko ES, Khaitov MR, Fomina D, Beltiukov E, van Hage M, Grönlund H, Valenta R, Karaulov A, Curin M. Allergy. 2020 Apr 17. doi: 10.1111/all.14325. [Epub ahead of print]
Current perspective on eicosanoids in asthma and allergic diseases - EAACI Task Force consensus report, part I. Sokolowska M, Rovati GE, Diamant Z, Untersmayr E, Schwarze J, Lukasik Z, Sava F, Angelina A, Palomares O, Akdis C, O'Mahony L, Sanak M, Dahlen SE, Woszczek G. Allergy. 2020 Apr 12. doi: 10.1111/all.14295. [Epub ahead of print]
A novel whole blood gene expression signature for asthma, dermatitis, and rhinitis multimorbidity in children and adolescents. Lemonnier N, Melén E, Jiang Y, Joly S, Ménard C, Aguilar D, Acosta-Perez E, Bergström A, Boutaoui N, Bustamante M, Canino G, Forno E, Ramon González J, Garcia-Aymerich J, Gruzieva O, Guerra S, Heinrich J, Kull I, Ibarluzea Maurolagoitia J, Santa-Marina Rodriguez L, Thiering E, Wickman M, Akdis C, Akdis M, Chen W, Keil T, Koppelman GH, Siroux V, Xu CJ, Hainaut P, Standl M, Sunyer J, Celedón JC, Maria Antó J, Bousquet J. Allergy. 2020 Apr 11. doi: 10.1111/all.14314. [Epub ahead of print]
Changes of DNA methylation are associated with changes in lung function during adolescence. Sunny SK, Zhang H, Rezwan FI, Relton CL, Henderson AJ, Merid SK, Melén E, Hallberg J, Arshad SH, Ewart S, Holloway JW. Respir Res. 2020 Apr 7;21(1):80. doi: 10.1186/s12931-020-01342-y.
The use of short-acting beta-2 adrenergic receptor agonists for asthma increased among Finnish and Swedish children from 2006 to 2017. Kivistö JE, Karjalainen J, Huhtala H, Protudjer JLP. Acta Paediatr. 2020 Apr 7. doi: 10.1111/apa.15288. [Epub ahead of print]
Urinary Exosomes from Bladder Cancer Patients Show a Residual Cancer Phenotype despite Complete Pathological Downstaging. Hiltbrunner S, Mints M, Eldh M, Rosenblatt R, Holmström B, Alamdari F, Johansson M, Veerman RE, Winqvist O, Sherif A, Gabrielsson S. Sci Rep. 2020 Apr 6;10(1):5960. doi: 10.1038/s41598-020-62753-x.
Biologicals in atopic disease in pregnancy: an EAACI position paper. Pfaller B, Yepes-Nuñez JJ, Agache I, Akdis CA, Alsalamah M, Bavbek S, Bossios A, Boyman O, Chaker A, Chan S, Chatzipetrou A, du Toit G, Jutel M, Kauppi P, Kolios A, Li C, Matucci A, Marson A, Bendien S, Palomares O, Rogala B, Szepfalusi Z, Untersmayr E, Vultaggio A, Eiwegger T. Allergy. 2020 Mar 18. doi: 10.1111/all.14282. [Epub ahead of print]
Early-life antibiotic use and risk of asthma and eczema: results of a discordant twin study. Slob EMA, Brew BK, Vijverberg SJH, Kats CJAR, Longo C, Pijnenburg MW, van Beijsterveldt TCEM, Dolan CV, Bartels M, Magnusson P, Lichtenstein P, Gong T, Koppelman GH, Almqvist C, Boomsma DI, Maitland-van der Zee AH. Eur Respir J. 2020 Apr 23;55(4). pii: 1902021. doi: 10.1183/13993003.02021-2019. Print 2020 Apr.
Noise exposure and childhood asthma up to adolescence. Wallas AE, Eriksson C, Ögren M, Pyko A, Sjöström M, Melén E, Pershagen G, Gruzieva O. Environ Res. 2020 Jun;185:109404. doi: 10.1016/j.envres.2020.109404. Epub 2020 Mar 19.
Acute wheeze-specific gene module shows correlation with vitamin D and asthma medication. Katayama S, Stenberg Hammar K, Krjutškov K, Einarsdottir E, Hedlin G, Kere J, Söderhäll C. Eur Respir J. 2020 Jan 23;55(1). pii: 1901330. doi: 10.1183/13993003.01330-2019. Print 2020 Jan.
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